Download Anxiety and Anxiolytic Drugs by Florian Holsboer, Andreas Ströhle PDF

Toxicology

By Florian Holsboer, Andreas Ströhle

ISBN-10: 3540225684

ISBN-13: 9783540225683

The current quantity provides a complete evaluate at the present country of simple and medical learn on Anxiety and Anxiolytic medicines . utilizing newly built tools and methods researchers are actually commencing to comprehend the molecular mechanisms of tension, anxiousness issues and their therapy. In parallel, new drug objectives were generated and the 1st scientific reports with new compounds were all started. In 20 chapters written by way of quite a few specialists within the box accomplished info on all proper issues is equipped.

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Trends Neurosci 21:317–323 Wehner JM, Radcliffe RA, Bowers BJ (2001) Quantitative genetics and mouse behavior. Annu Rev Neurosci 24:845–867 Weinberger NM (1998) Physiological memory in primary auditory cortex: characteristics and mechanisms. Neurobiol Learn Mem 70:226–251 Welzl H, D’Adamo P, Lipp HP (2001) Conditioned taste aversion as a learning and memory paradigm. Behav Brain Res 125:205–213 Whishaw IQ, Metz GA, Kolb B, Pellis SM (2001) Accelerated nervous system development contributes to behavioral efficiency in the laboratory mouse: a behavioral review and theoretical proposal.

The characterisation of memory-related genes and proteins belongs to the hot spots of current memory research (D’Agata and Cavallaro 2002). Respective studies in the field of aversive memories employ different molecular biological methods including in situ hybridisation (Ressler et al. 2002), differential display (Huang et al. 1998), subtractive hybridisation (Stork et al. 2001) and DNA microarrays (Kida et al. 2002). Most critical for the correct interpretation 18 C. T. Wotjak of the data are the selections of appropriate controls, as unspecific changes in gene expression may occur already from handling of the animals and exposure to the test context.

Clin Psychol Rev 11:123–140 Bouton ME, Nelson JB, Rosas JM (1999) Stimulus generalization, context change, and forgetting. Psychol Bull 125:171–186 Bouton ME, Mineka S, Barlow DH (2001) A modern learning theory perspective on the etiology of panic disorder. Psychol Rev 108:4–32 Braunewell KH, Manahan-Vaughan D (2001) Long-term depression: a cellular basis for learning? Rev Neurosci 12:121–140 Brown SD, Balling R (2001) Systematic approaches to mouse mutagenesis. Curr Opin Genet Dev 11:268–273 Bucan M, Abel T (2002) The mouse: genetics meets behaviour.

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